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    Learn/Histology/Stomach — fundic mucosa with parietal + chief cells
    Normal·GI·Stomach

    Stomach — fundic mucosa with parietal + chief cells

    Stain: H&E·Magnification: 40x·Tissue: Gastric mucosa·3 labeled regions
    Stomach — fundic mucosa with parietal + chief cells histology — GI, Stomach, H&E
    Wikimedia Commons · File:Histology of normal antral mucosa.png · https://commons.wikimedia.org/wiki/File:Histology_of_normal_antral_mucosa.png (CC-licensed)
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    Description

    Surface mucous cells line the lumen; gastric glands extend downward containing parietal (HCl + IF) and chief (pepsinogen) cells.

    Labeled regions (3)

    1. 1
      Surface mucous cell

      Tall columnar with apical mucin.

    2. 2
      Parietal cell

      Bright pink, round; H+/K+-ATPase target of PPIs; loss → pernicious anemia.

    3. 3
      Chief cell

      Basal, basophilic; secretes pepsinogen.

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