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Normal·GI·Stomach

Stomach — fundic mucosa with parietal + chief cells

Stain: H&E·Magnification: 40x·Tissue: Gastric mucosa·3 labeled regions
Stomach — fundic mucosa with parietal + chief cells histology — GI, Stomach, H&E
Wikimedia Commons · File:Histology of normal antral mucosa.png · https://commons.wikimedia.org/wiki/File:Histology_of_normal_antral_mucosa.png (CC-licensed)
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Description

Surface mucous cells line the lumen; gastric glands extend downward containing parietal (HCl + IF) and chief (pepsinogen) cells.

Labeled regions (3)

  1. 1
    Surface mucous cell

    Tall columnar with apical mucin.

  2. 2
    Parietal cell

    Bright pink, round; H+/K+-ATPase target of PPIs; loss → pernicious anemia.

  3. 3
    Chief cell

    Basal, basophilic; secretes pepsinogen.

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