Normal·GI·Small intestine
Simple columnar epithelium — small intestine villus
Stain: H&E·Magnification: 40x·Tissue: Simple columnar with microvilli·4 labeled regions
Wikimedia Commons · File:Small intestine low mag.jpg · https://commons.wikimedia.org/wiki/File:Small_intestine_low_mag.jpg (CC-licensed)
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Tall absorptive enterocytes line the villus surface. Apical brush border (microvilli) maximizes surface area; scattered goblet cells secrete mucin.
Labeled regions (4)
- 1Enterocyte (absorptive cell)
Tall columnar with eosinophilic apical border; expresses brush-border disaccharidases.
- 2Goblet cell
Mucin-filled apical cytoplasm; PAS-positive. Scattered among enterocytes.
- 3Brush border (microvilli)
Actin-based projections; site of disaccharidases (lactase first lost in injury).
- 4Lamina propria
Loose connective tissue core of villus; contains capillaries, lacteal, immune cells.
