Normal·GI·Liver
Liver — classic hepatic lobule
Stain: H&E·Magnification: 20x·Tissue: Hepatic parenchyma·4 labeled regions

Wikimedia Commons · File:Portal triad.JPG · https://commons.wikimedia.org/wiki/File:Portal_triad.JPG (CC-licensed)
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Hexagonal lobule with central vein at the center and portal triads at the corners. Hepatocytes arranged in plates one cell thick.
Labeled regions (4)
- 1Central vein
Drains toward hepatic veins → IVC.
- 2Portal triad
Hepatic artery + portal vein + bile duct.
- 3Hepatocyte
Polygonal cell with prominent nucleolus; pink granular cytoplasm.
- 4Sinusoid
Fenestrated capillaries between hepatocyte plates; Kupffer cells reside here.
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