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    Learn/Histology/Liver — classic hepatic lobule
    Normal·GI·Liver

    Liver — classic hepatic lobule

    Stain: H&E·Magnification: 20x·Tissue: Hepatic parenchyma·4 labeled regions
    Liver — classic hepatic lobule histology — GI, Liver, H&E
    Wikimedia Commons · File:Portal triad.JPG · https://commons.wikimedia.org/wiki/File:Portal_triad.JPG (CC-licensed)
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    Description

    Hexagonal lobule with central vein at the center and portal triads at the corners. Hepatocytes arranged in plates one cell thick.

    Labeled regions (4)

    1. 1
      Central vein

      Drains toward hepatic veins → IVC.

    2. 2
      Portal triad

      Hepatic artery + portal vein + bile duct.

    3. 3
      Hepatocyte

      Polygonal cell with prominent nucleolus; pink granular cytoplasm.

    4. 4
      Sinusoid

      Fenestrated capillaries between hepatocyte plates; Kupffer cells reside here.

    More gi histology

    Esophagus — non-keratinized stratified squamous epithelium
    Esophagus — non-keratinized stratified squamous epithelium
    Esophagus
    Submandibular salivary gland — mixed acini + serous demilunes
    Submandibular salivary gland — mixed acini + serous demilunes
    Salivary gland
    Simple columnar epithelium — small intestine villus
    Simple columnar epithelium — small intestine villus
    Small intestine
    Pancreas — exocrine acini + endocrine islet
    Pancreas — exocrine acini + endocrine islet
    Pancreas
    Stomach — fundic mucosa with parietal + chief cells
    Stomach — fundic mucosa with parietal + chief cells
    Stomach