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    Learn/Histology/Pancreas — exocrine acini + endocrine islet
    Normal·GI·Pancreas

    Pancreas — exocrine acini + endocrine islet

    Stain: H&E·Magnification: 20x·Tissue: Mixed exo/endocrine·3 labeled regions
    Pancreas — exocrine acini + endocrine islet histology — GI, Pancreas, H&E
    Wikimedia Commons · File:Langerhanssche Insel.jpg · https://commons.wikimedia.org/wiki/File:Langerhanssche_Insel.jpg (CC-licensed)
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    Description

    Dark-pink zymogen-rich acini dominate; pale-staining islets of Langerhans sit scattered among them — endocrine cells producing insulin (β), glucagon (α), somatostatin (δ).

    Labeled regions (3)

    1. 1
      Acinus (exocrine)

      Cluster of pyramidal cells with apical zymogen granules.

    2. 2
      Islet of Langerhans

      Pale, well-circumscribed cluster — endocrine pancreas.

    3. 3
      Intercalated duct (centroacinar cell)

      Light-staining cell at center of acinus; secretes HCO3⁻.

    More gi histology

    Esophagus — non-keratinized stratified squamous epithelium
    Esophagus — non-keratinized stratified squamous epithelium
    Esophagus
    Liver — classic hepatic lobule
    Liver — classic hepatic lobule
    Liver
    Submandibular salivary gland — mixed acini + serous demilunes
    Submandibular salivary gland — mixed acini + serous demilunes
    Salivary gland
    Simple columnar epithelium — small intestine villus
    Simple columnar epithelium — small intestine villus
    Small intestine
    Stomach — fundic mucosa with parietal + chief cells
    Stomach — fundic mucosa with parietal + chief cells
    Stomach