Normal·Reproductive·Uterus
Endometrium — secretory phase
Stain: H&E·Magnification: 20x·Tissue: Endometrial glands + stroma·3 labeled regions
Wikimedia Commons · File:Endometrium_Secretory_20x1.jpg · https://commons.wikimedia.org/wiki/File:Endometrium_Secretory_20x1.jpg (CC-licensed)
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Post-ovulation, progesterone-driven endometrium. Glands become tortuous + sawtoothed with sub-nuclear / supranuclear vacuoles, stroma becomes edematous + decidualized — preparing for implantation.
Labeled regions (3)
- 1Tortuous secretory glands
Coiled + sawtoothed glands with luminal secretions. Hallmark of progesterone effect after ovulation.
- 2Subnuclear vacuoles
Glycogen-rich clear vacuoles beneath gland nuclei — earliest sign of ovulation having occurred.
- 3Edematous stroma
Loose, pale stroma between glands. Late secretory phase: decidualization with plump cells.
