MSK

A boards-focused Rheumatoid Arthritis lesson tracing pathophysiology (citrullination, anti-CCP/RF, pannus, RANKL erosions) through classic presentation, diagnosis (autoantibodies, inflammatory synovial fluid, erosive imaging), and treat-to-target DMARD management. Emphasizes vignette buzzwords, RA-vs-OA contrasts, and next-best-step decisions like TB and hepatitis screening before TNF inhibitors.

A board-focused MSK/rheumatology lesson contrasting osteoarthritis (degenerative), gout (MSU crystals), and pseudogout (CPPD crystals) across pathophysiology, presentation, synovial fluid and imaging, and next-best-step management. Emphasizes arthrocentesis to exclude septic arthritis, birefringence patterns, negative autoantibodies, and the rule against starting urate-lowering therapy during an acute flare.

Board-focused SLE and antiphospholipid syndrome: the type III/type II immune-complex pathophysiology, buzzword presentations (malar rash, nonerosive arthritis, Libman–Sacks), the autoantibody panel and synovial-fluid/imaging clues that clinch the diagnosis, and next-best-step management — plus APS's clotting paradox (prolonged aPTT that won't correct, false-positive VDRL) and its warfarin-not-DOAC treatment.

A high-yield overview of the HLA-B27-associated seronegative spondyloarthropathies (ankylosing spondylitis, reactive, psoriatic, and enteropathic arthritis), covering shared IL-23/IL-17 pathophysiology, classic vignette buzzwords, sacroiliac imaging and synovial-fluid workup, and the NSAID → DMARD → biologic management ladder with board-style next-best-step decisions.

A boards-focused tour of the systemic vasculitides organized by Chapel Hill vessel size, pairing each disease with its antibody, buzzwords, and imaging. It drills the high-yield next-best-step decisions—steroids-before-biopsy in giant cell arteritis and rituximab-based induction in ANCA-associated disease.

A Step 1–focused, clinically verified lesson on three antibody-defined connective tissue diseases — Sjögren, systemic sclerosis (limited/CREST vs diffuse), and MCTD — emphasizing signature autoantibodies, buzzword vignettes, and next-best-step decisions like ACE inhibitors for scleroderma renal crisis. Includes a comparison table, the standard CREST mnemonic, and two verified Commons images.

A board-focused MSK/rheumatology lesson on osteomyelitis and septic arthritis, moving from pathophysiology and organism-by-scenario buzzwords through synovial fluid analysis, imaging, and next-best-step management. Emphasizes arthrocentesis as the pivotal test, empiric vancomycin ± ceftriaxone, and crystal/reactive-arthritis mimics.

A boards-focused walk through primary bone tumors, sorted by the three clues that crack every vignette — patient age, location within the bone, and radiographic buzzwords — with osteosarcoma and Ewing sarcoma vignettes and the mandatory biopsy-before-treatment workup. Emphasizes imaging signs, genetics, RANKL/PGE2 mechanisms, and next-best-step decisions.