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    Learn/Histology/Peripheral nerve — cross section
    Normal·Neurology·Peripheral nerve

    Peripheral nerve — cross section

    Stain: H&E·Magnification: 20x·Tissue: Mixed nerve fascicles·4 labeled regions
    Peripheral nerve — cross section histology — Neurology, Peripheral nerve, H&E
    Wikimedia Commons · File:Peripheral nerve, cross section.jpg · https://commons.wikimedia.org/wiki/File:Peripheral_nerve,_cross_section.jpg (CC-licensed)
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    Description

    Bundles of myelinated + unmyelinated axons surrounded by three connective tissue sheaths. Each axon is wrapped by a Schwann cell.

    Labeled regions (4)

    1. 1
      Axon

      Central pale dot.

    2. 2
      Myelin sheath

      Schwann cell plasma membrane wraps the axon (PNS).

    3. 3
      Endoneurium

      Loose CT around individual axons.

    4. 4
      Perineurium

      Dense epithelioid sheath around each fascicle; blood–nerve barrier.

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