Normal·Neurology·Peripheral nerve

Peripheral nerve — cross section

Stain: H&E·Magnification: 20x·Tissue: Mixed nerve fascicles·4 labeled regions
Peripheral nerve — cross section histology — Neurology, Peripheral nerve, H&E
Wikimedia Commons · File:Peripheral nerve, cross section.jpg · https://commons.wikimedia.org/wiki/File:Peripheral_nerve,_cross_section.jpg (CC-licensed)
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Description

Bundles of myelinated + unmyelinated axons surrounded by three connective tissue sheaths. Each axon is wrapped by a Schwann cell.

Labeled regions (4)

  1. 1
    Axon

    Central pale dot.

  2. 2
    Myelin sheath

    Schwann cell plasma membrane wraps the axon (PNS).

  3. 3
    Endoneurium

    Loose CT around individual axons.

  4. 4
    Perineurium

    Dense epithelioid sheath around each fascicle; blood–nerve barrier.

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