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    Learn/Histology/Transitional epithelium (urothelium) — urinary bladder
    Normal·Renal/Urinary·Bladder

    Transitional epithelium (urothelium) — urinary bladder

    Stain: H&E·Magnification: 40x·Tissue: Transitional epithelium·3 labeled regions
    Transitional epithelium (urothelium) — urinary bladder histology — Renal/Urinary, Bladder, H&E
    Wikimedia Commons · File:Harnblase Urothel.png · https://commons.wikimedia.org/wiki/File:Harnblase_Urothel.png (CC-licensed)
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    Description

    Stretchable multi-layer epithelium unique to the urinary tract. Apical 'umbrella cells' have specialized plaques that resist urine.

    Labeled regions (3)

    1. 1
      Umbrella cell

      Large dome-shaped luminal cell with specialized uroplakin plaques.

    2. 2
      Intermediate cells

      Pear-shaped middle layers; allow stretching.

    3. 3
      Basal cells

      Cuboidal anchoring layer on basement membrane.

    More renal/urinary histology

    Smooth muscle — bladder wall (detrusor)
    Smooth muscle — bladder wall (detrusor)
    Bladder
    Renal cortex — glomerulus + tubules
    Renal cortex — glomerulus + tubules
    Kidney