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    Learn/Histology/Lung — alveolar parenchyma
    Normal·Respiratory·Lung

    Lung — alveolar parenchyma

    Stain: H&E·Magnification: 40x·Tissue: Alveolar·4 labeled regions
    Lung — alveolar parenchyma histology — Respiratory, Lung, H&E
    Wikimedia Commons · File:Alveolar sac.JPG · https://commons.wikimedia.org/wiki/File:Alveolar_sac.JPG (CC-licensed)
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    Description

    Open spaces lined by Type I pneumocytes (thin, gas exchange) and Type II (cuboidal, surfactant). Macrophages roam the airspaces.

    Labeled regions (4)

    1. 1
      Alveolar space

      Air-filled lumen.

    2. 2
      Type I pneumocyte

      Flat squamous cell covering ~97% of alveolar surface.

    3. 3
      Type II pneumocyte

      Cuboidal; surfactant + progenitor for type I.

    4. 4
      Alveolar macrophage

      Dust cell; can become 'heart failure cells' (hemosiderin-laden) in chronic LHF.

    More respiratory histology

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    Asthma — airway remodeling + eosinophilic inflammation
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    Pseudostratified ciliated columnar epithelium — trachea
    Pseudostratified ciliated columnar epithelium — trachea
    Trachea