Normal·Integumentary·Skin
Stratified squamous epithelium (keratinized) — thin skin
Stain: H&E·Magnification: 20x·Tissue: Stratified squamous epithelium, keratinized·5 labeled regions

Wikimedia Commons · File:Epidermis-delimited.JPG · https://commons.wikimedia.org/wiki/File:Epidermis-delimited.JPG (CC-licensed)
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Multiple cell layers terminating in a non-nucleated keratin layer. Protects against abrasion + dehydration; lines all dry external surfaces.
Labeled regions (5)
- 1Stratum corneum
Anucleate, keratinized squames; tough barrier layer.
- 2Stratum granulosum
Keratohyalin granules — final maturation step before death.
- 3Stratum spinosum
Polyhedral cells joined by desmosomes (spiny appearance).
- 4Stratum basale
Single cuboidal layer on basement membrane; mitotically active.
- 5Dermal papilla
Loose connective tissue projection into epidermis; carries vessels + nerves.
