Normal·Musculoskeletal·Skeletal muscle

Skeletal muscle — longitudinal section

Stain: H&E·Magnification: 40x·Tissue: Skeletal muscle·3 labeled regions
Skeletal muscle — longitudinal section histology — Musculoskeletal, Skeletal muscle, H&E
Wikimedia Commons · File:Musc est long 400.JPG by Ganímedes · https://commons.wikimedia.org/wiki/File:Musc_est_long_400.JPG (CC BY-SA 3.0)
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Description

Multinucleated fibers with peripheral nuclei and prominent striations. Each fiber is a single elongated cell; voluntary.

Labeled regions (3)

  1. 1
    Striations (A + I bands)

    Alternating dark (A) + light (I) bands from sarcomeric register.

  2. 2
    Peripheral nuclei

    Multiple nuclei pushed to the sarcolemma — pathognomonic for skeletal.

  3. 3
    Endomysium

    Delicate connective tissue surrounding each fiber.

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