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    Learn/Histology/Skeletal muscle — longitudinal section
    Normal·Musculoskeletal·Skeletal muscle

    Skeletal muscle — longitudinal section

    Stain: H&E·Magnification: 40x·Tissue: Skeletal muscle·3 labeled regions
    Skeletal muscle — longitudinal section histology — Musculoskeletal, Skeletal muscle, H&E
    Wikimedia Commons · File:Musc est long 400.JPG by Ganímedes · https://commons.wikimedia.org/wiki/File:Musc_est_long_400.JPG (CC BY-SA 3.0)
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    Description

    Multinucleated fibers with peripheral nuclei and prominent striations. Each fiber is a single elongated cell; voluntary.

    Labeled regions (3)

    1. 1
      Striations (A + I bands)

      Alternating dark (A) + light (I) bands from sarcomeric register.

    2. 2
      Peripheral nuclei

      Multiple nuclei pushed to the sarcolemma — pathognomonic for skeletal.

    3. 3
      Endomysium

      Delicate connective tissue surrounding each fiber.

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