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    Learn/Histology/Cardiac muscle — intercalated discs
    Normal·Cardiovascular·Myocardium

    Cardiac muscle — intercalated discs

    Stain: H&E·Magnification: 40x·Tissue: Cardiac muscle·3 labeled regions
    Cardiac muscle — intercalated discs histology — Cardiovascular, Myocardium, H&E
    Wikimedia Commons · File:Dogcardiacmuscle400.jpg · https://commons.wikimedia.org/wiki/File:Dogcardiacmuscle400.jpg (CC-licensed)
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    Description

    Striated branching fibers with central nuclei. Intercalated discs (gap junctions + desmosomes) couple cells electrically and mechanically — the functional syncytium of the heart.

    Labeled regions (3)

    1. 1
      Intercalated disc

      Stair-step junction — contains gap junctions, desmosomes, fascia adherens.

    2. 2
      Central nucleus

      Single, ovoid, central — distinguishes from skeletal (peripheral).

    3. 3
      Striations

      Sarcomeres confirm cardiac is striated, unlike smooth.

    More cardiovascular histology

    Atherosclerosis — fibrous cap + lipid core
    Atherosclerosis — fibrous cap + lipid core
    Artery (aorta/coronary)