Respiratory and GI Pharmacology
Sample questions
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A 13-year-old boy suffering from acute lymphoblastic leukemia was admitted to the hospital for the third cycle of anticancer therapy, which included high-dose methotrexate. Which of the following drugs should be given to the patient to counteract methotrexate toxicity?
A 2-year-old boy was brought to the emergency department after suffering two episodes of brownish vomit containing pills, followed by a large hematemesis. The mother, who was pregnant, suspected her son had ingested several tablets of her medication. Physical examination showed a lethargic and cyanotic child complaining of abdominal pain. Vital signs were blood pressure 80/50 mm Hg (normal for 2 years 100/65 mm Hg), pulse 130 bpm (normal for 2 years 115 bpm) respirations 30/min (normal at 2 years 24/min). Laboratory values indicated severe metabolic acidosis. Which of the following drugs would be most appropriate for this child?
A 66-year-old woman complained to her physician of bleeding gums. The woman had been receiving her third cycle of chemotherapy for metastatic ovarian cancer. A blood analysis showed the following results: red blood cell count 3.2 × 106/mm3 (normal, female 3.5−5.5 × 106/mm3), mean corpuscular volume 96 fL (normal 80−100 fL), hemoglobin 9 g/dL (normal, female > 12 g/dL), neutrophil count 4600/mm3 (normal 3000−7000/mm 3), platelet count 7000/mm3 (normal 130,000−400,000/mm 3). A hematopoietic agent was administered intravenously. Which of the following drugs would be appropriate for this patient?
Sample flashcards
A 13-year-old boy suffering from acute lymphoblastic leukemia was admitted to the hospital for the third cycle of anticancer therapy, which included high-dose methotrexate. Which of the following drugs should be given to the patient to counteract methotrexate toxicity? You picked: A. Folic acid
A 45-year-old man had been suffering from chronic obstructive pulmonary disease that was not adequately controlled by inhaled salmeterol and ipratropium. His physician decided to add a third drug that is thought to act by multiple mechanisms, including inhibition of phosphodiesterase 4 in in ammatory cells and enhancement of histone deacetylation. Which of the following drugs was most likely added to the patient’s therapeutic regimen? You picked: A. Ipratropium
A 70-year-old woman complained to her physician of obstinate constipation. The physician prescribed a laxative that acts in the colon by absorbing water into the fecal contents, thus promoting peristalsis about 1 or 2 days after administration. Which of the following drugs was most likely prescribed? You picked: B. Docusate
A 45-year-old man with a long history of chronic severe asthma was admitted to the emergency department with extreme dyspnea and wheezing. His medical history was signi cant for a recently diagnosed duodenal ulcer. Current medications included inhaled albuterol, beclomethasone, and ipratropium on a chronic basis. Vital signs were heart rate 130 bpm, blood pressure 140/90 mm Hg, respirations 30/min. An electrocardiogram showed sinus tachycardia with occasional premature ventricular contractions.… You picked: D. Ipratropium dosage and the disease-induced hypoxemia
A 9-year-old girl with a long history of cystic brosis presented to the hospital because of worsening of respiratory symptoms. An appropriate therapy was prescribed that included inhaled dornase alfa. Which of the following best explains the mechanism of action of dornase alfa in the patient’s disease? You picked: A. Supports bactericidal activity against Pseudomonas aeruginosa
A 53-year-old woman complained to her physician that the drug she was taking did not work and that she was still suffering from obstinate constipation. The woman had a long history of irritable bowel syndrome and took several drugs in the past with limited success. She was presently taking lactulose. The physician decided to try another drug recently approved for irritable bowel syndrome with constipation in adult women. The drug is a prostanoid derivative that acts by opening type 2 chloride… You picked: D. Metoclopramide
FAQ
What's covered in the Respiratory and GI Pharmacology topic?
Respiratory and GI Pharmacology covers high-yield mechanisms, clinical presentations, diagnostic workup, and management — drawn from First Aid, Pathoma, and the NBME content outline.
How many practice questions does Respiratory and GI Pharmacology have?
85 board-style multiple-choice questions and 8 spaced-repetition flashcards. Sign up free to drill them with adaptive difficulty and a Socratic AI tutor that explains every wrong answer.
Is Respiratory and GI Pharmacology on USMLE Step 1 or Step 2 CK?
Respiratory and GI Pharmacology appears on both Step 1 (foundational mechanisms) and Step 2 CK (clinical decision-making). Our questions are tagged by exam target so you can filter to just the Step you're studying.
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