Cardiovascular Pharmacology

A 63-year-old woman was found to have a third-degree atrioventricular block. The woman, who had been suffering from stage C heart failure, had been receiving captopril, furosemide, and digoxin for 2 months, and the disease was well controlled. The physician believed that the block was due to digoxin therapy. Which of the following would be an appropriate therapeutic adjustment for this patient? You picked: E. Add dobutamine and decrease the digoxin dose

A 48-year-old man was brought to the emergency department because of severe chest pain that had been ongoing for over 3 hours. The man had been suffering from chronic stable exertional angina for 1 year and from duodenal ulcer for 3 months. His current medication included isosorbide mononitrate and verapamil for angina and famotidine for duodenal ulcer. One week earlier, the patient stopped the antianginal medications because he had not had anginal attacks during the past month. Which of the… You picked: E. Re ex tachycardia due to nitrate therapy

A 52-year-old woman suffering from hypertension still had a blood pressure of 156/92 mm Hg after 3 months of therapy with hydrochlorothiazide and losartan. Her physician decided to add a third drug that acts by decreasing central sympathetic out flow. Which of the following adverse eeffects was most likely to occur after a few days of therapy with the new drug? You picked: A. Severe postural hypotension

A 57-year-old man admitted to the coronary unit after coronary bypass surgery developed increasing ectopic beats followed by sustained tachycardia. An electrocardiogram showed a frequency of 170 bpm, wide QRS complexes, and atrioventricular dissociation. An intravenous (IV) loading dose of an appropriate drug was given, then an IV infusion of the same drug was started. Which of the following drugs was most likely administered? You picked: C. Quinidine

A 51-year-old man suffering from hyperlipidemia was screened with a lipoprotein pro le during a follow-up medical evaluation. He was found to have a low-density lipoprotein (LDL) cholesterol level of 440 mg/dL (normal <130 mg/ dL) despite many months of lovastatin therapy. Triglyceride levels were 120 mg/dL. The patient had been suffering from type I diabetes for 15 years. Because a substantial reduction of LDL cholesterol was needed, a combination of two antihyperlipidemic drugs was… You picked: B. Lovastatin and niacin

A 63-year-old man was admitted to the emergency department because of a 12-hour history of dyspnea and bradycardia. He was taking propranolol, captopril, furosemide, and amiloride because of a previous myocardial infarction, as well as ibuprofen for osteoarthritis. Physical examination showed the patient was in respiratory distress with the following vital signs: blood pressure 150/86 mm Hg; heart rate 40 bpm; respirations 20/min. A lab analysis was ordered. Which of the following substances… You picked: A. Sodium