Antimicrobial Pharmacology

A 56-year-old man recently had a routine blood test during his annual checkup. The test showed a white blood cell count of 42,000/mm3 (normal 4500−11,000/mm3). The only pertinent physical nding was splenomegaly. A bone marrow aspirate revealed hypercellular marrow with 15% blasts, and cytogenetic analysis found the presence of the Philadelphia chromosome. A diagnosis was made, and a therapy was started. Which of the following drugs would be most appropriate to include in the patient’s therapeutic regimen?

A 56-year-old woman with a long history of heavy smoking presented with cough, fever, chest pain, and bloody sputum. A chest x-ray revealed a 3.5-cm (1.4-in.) hilar mass, and a transbronchial biopsy showed in ltrating groups of anaplastic small cells with hyperchromatic nuclei and no nucleoli. Which of the following drugs was most likely appropriately included in the therapeutic regimen of this patient?

A 53-year-old woman recently diagnosed with ovarian cancer started a treatment that included paclitaxel. The patient was most likely at increased risk of which of the following adverse eeffects as a result of her therapy?